Drug makers AstraZeneca and Targacept say they have abandoned plans to seek regulatory approval for a drug intended to treat major depressive disorder.

AstraZeneca PLC said Tuesday that the drug TC-5214 did not perform as hoped in an eight-week trial compared to a placebo.

It's a quintessentially Cuban experience: Capping off a meal with a snifter of rum and an aromatic cigar.

This Caribbean nation is renowned around the world for its pungent Cohibas, Montecristos and Romeo y Julietas, but on the island, stogie-lovers are increasingly being told to take it outside.

IMF chief Christine Lagarde said Tuesday the global economy has moved back from the "abyss" but that there is still serious weakness in the world financial system.

Lagarde, visiting New Delhi for a two-day trip to attend a conference and meet leaders, said the world financial situation is not as grave as at the start of this year.

Oil prices fell to near $107 a barrel Tuesday in Asia, slipping from close to 10-month highs ahead of new data on the U.S. economy.

Benchmark oil for April delivery was down 80 cents to $107.29 a barrel at late afternoon Singapore time in electronic trading on the New York Mercantile Exchange. The contract rose $1.03 to settle at $108.09 in New York on Monday.

Iran's supreme leader said Tuesday that more support for domestic industrial production can counter Western sanctions over Tehran's nuclear program.

The statement by Ayatollah Ali Khamenei marking the Iranian new year is the latest in a series of displays of defiance by the country's senior leadership against the pressures — ranging from sanctions to the option of future military strikes — placed on Iran by the U.S. and the West.

Microsoft says it's not coming out with a new Xbox gaming console anytime soon.

Some video game players had hoped that Microsoft Corp. would unveil an upgrade at the E3 Expo in June, a big, yearly video game conference in Los Angeles where game makers show off new wares and titles.

When Justin Bassett interviewed for a new job, he expected the usual questions about experience and references. So he was astonished when the interviewer asked for something else: his Facebook username and password.

Bassett, a New York City statistician, had just finished answering a few character questions when the interviewer turned to her computer to search for his Facebook page. But she couldn't see his private profile. She turned back and asked him to hand over his login information.

400-pound (180-kilogram) gorilla that escaped from its cage at an upstate New York zoo and bit a zookeeper has been captured in a zookeepers' lounge and has been tranquilized.

The Buffalo Zoo says a 24-year-old male gorilla named Koga got out of his cage into an aisle where the keeper was working Monday morning and bit her on the hand and calf.

A British math teacher was convicted Monday of harassing his German neighbors with loud wartime music and Nazi salutes.

Prosecutors said Geoffrey Butler, 54, caused Reinhard and Kathryn Wendt four years of misery, among other things miming a Nazi salute and a Hitler mustache, playing a Winston Churchill speech and blasting patriotic British songs like "Rule Britannia."

A man who made comments about his estranged wife on his Facebook page and was threatened with jail unless he posted daily apologies for a month won't be locked up even though he stopped making amends early.

Mark Byron agreed to begin posting the apology last month to avoid jail but later said the ruling violated his freedom of speech. He stopped posting the apology after 26 days, but Judge Jon Sieve, of Hamilton County Domestic Relations Court, determined Monday that he had posted it long enough, and Byron wasn't jailed.