Israel's Prime Minister Benjamin Netanyahu urged calm after a bus driver ran over and killed a teenage boy Tuesday night during a protest in Jerusalem against a law seeking to draft the ultra-Orthodox community into Israel's military.

"I call for restraint to prevent the mood from becoming further inflamed so that, heaven forbid, we do not have additional tragedies," Netanyahu said in a statement early Wednesday, adding that the death would be thoroughly investigated.

The United Nations said on Wednesday that decades of discrimination and segregation of Palestinians in the West Bank by Israel were intensifying and creating a kind of "apartheid system".

Rights chief Volker Turk said there was "a systematic asphyxiation of the rights of Palestinians in the West Bank", creating a "particularly severe form of racial discrimination and segregation, that resembles the kind of apartheid system we have seen before".

A council fighting against Yemen's Houthi rebels said Wednesday that it had expelled the leader of a separatist movement and charged him with treason after he reportedly declined to travel to Saudi Arabia for talks.

The latest upheaval in southern Yemen is revealing a growing divide among the Persian Gulf powers, cracking the coalition fighting the Iran-aligned Houthis. Longstanding differences between Saudi Arabia and the United Arab Emirates — from Sudan to energy policy — have spilled into Yemen, where they back rival factions. The rift has deepened strains between the two neighbors, who officially share the goal of countering the Houthis, in control of the capital, Sanaa, since 2014.

Civilians were fleeing Kurdish neighborhoods of Aleppo on Wednesday after the Syrian army declared them "closed military zones", amid ongoing fighting with Kurdish-led forces.

The Syrian army said that Aleppo's Kurdish neighborhoods will be considered "closed military zones" as of 3.00pm (1200 GMT) on Wednesday, creating "humanitarian corridors" for civilians to leave through beforehand.

The deadliest clashes so far broke out Tuesday between Syrian government forces and Kurdish fighters in a contested area of the northern city of Aleppo, as efforts to merge the U.S.-backed Syrian Democratic Forces with the national army have shown little progress.

Syria 's state-run SANA news agency said a soldier was killed and three others were wounded in an attack by the SDF. State TV later reported that three civilians, including two women, were killed and others were wounded, including two children, in shelling of a residential area that it blamed on the SDF. SANA also said nine Aleppo Directorate of Agriculture employees were wounded by SDF shelling that hit its office.

Hundreds of tourists are stuck on the Yemeni island of Socotra after flights were halted over clashes on the mainland, two officials and a travel agency told AFP Monday.

The island's deputy governor for culture and tourism, Yahya bin Afrar, told AFP: "We have more than 400 foreign tourists... their flights have been suspended." Another local government official gave a similar figure.

Syrian and Israeli officials are set to resume U.S.-mediated talks in Paris in hopes of reaching a security agreement to defuse tensions between the two countries, a Syrian official said Monday.

The official, who spoke on condition of anonymity because he was not authorized to speak publicly, told The Associated Press that the delegation on the Syrian side will be headed by Foreign Minister Asaad al-Shibani and the head of the General Intelligence Directorate, Hussein Salameh.

Israeli authorities have told the Supreme Court that a ban on international media access to Gaza should remain in place, arguing it is necessary for security reasons, according to a government submission filed by the public prosecutor.

"Even at this time, entry of journalists into the Gaza Strip without escort, as requested in the petition, should not be permitted," said the government submission, a copy of which was obtained by AFP. "This is for security reasons, based on the position of the defence establishment, which maintains that a security risk associated with such entry still exists."

Israel's decision to revoke the licenses of more than three dozen humanitarian organizations this week has aid groups scrambling to grapple with what this means for their operations in Gaza and their ability to help tens of thousands of struggling Palestinians.

The 37 groups represent some of the most prominent of the more than 100 independent nongovernmental organizations working in Gaza, alongside United Nations agencies. Those banned include Doctors Without Borders, the Norwegian Refugee Council, Oxfam and Medical Aid for Palestinians.

Iran accused Israel on Monday of trying to undermine its national unity after Israeli Prime Minister Benjamin Netanyahu expressed support for protests in the Islamic republic.

"The Zionist regime (Israel) is determined to exploit the slightest opportunity to sow division and undermine our national unity, and we must remain vigilant," foreign ministry spokesman Esmail Baqaei said at a weekly press conference, before accusing Israeli and US leaders of "incitement to violence".