Brazilian forward Vinicius has issued a public apology to Real Madrid after his angered reaction to being substituted during a tense 2-1 win over arch-rival Barcelona at the weekend.

Barcelona midfielder Pedri will be sidelined for several weeks with the torn bicep leg injury he picked up in a 2-1 defeat at Real Madrid this weekend, his club announced.

The World Health Organization said Wednesday it was appalled at reports of more than 460 people being killed at a hospital in the Sudanese city of El-Fasher, recently taken over by paramilitaries.

Mediator Qatar said Wednesday it expected a US-backed ceasefire to hold in Gaza despite a "violation" as Israel carried out strikes in response to Palestinian fire.

Canada's central bank cut its key lending rate to 2.25 percent on Wednesday, saying that while the economy has shown resilience in response to President Donald Trump's trade war, "the impact is becoming more evident."

Russia has successfully tested a nuclear-capable, nuclear-powered underwater drone, President Vladimir Putin said Wednesday, defying US President Donald Trump's warnings with Moscow's second test of a new nuclear weapons system in just a few days.

The U.S. military confirmed Wednesday it was reducing its presence on NATO's eastern flank, but denied the move amounted to an American withdrawal from Europe.

German Foreign Minister Johann Wadephul on Wednesday expressed "deep concern" after the deadliest night of bombing in Gaza since a U.S.-brokered truce went into effect earlier this month.

Gaza's civil defense agency said the strikes had killed more than 100 people, including at least 35 children, a toll confirmed by an AFP tally of medical sources at five hospitals in Gaza.

Israel has banned the International Committee of the Red Cross (ICRC) for visiting Palestinian prisoners detained under a law targeting "illegal combatants", Defense Minister Israel Katz said on Wednesday.

"The opinions presented to me leave no doubt that Red Cross visits to terrorists in prisons would seriously harm the state's security. The safety of the state and our citizens comes first," Katz said, according to a statement from his office.

U.S. President Donald Trump on Wednesday said a trade deal with South Korea would be finalized soon, ahead of a meeting with the country's President Lee Jae Myung later in the day.

"Our deal with the Republic of Korea will be finalized very soon," he told delegates at the APEC CEO summit in the South Korean city of Gyeongju.