Iran's Revolutionary Guards said Sunday that the country's forces could fight an intense war for six months against the United States and Israel, which said it struck Tehran's commanders at a seaside hotel in the heart of Beirut.

As the conflict spilled into its second week, the regional repercussions spiraled, with Saudi Arabia intercepting a wave of drones headed for targets including the diplomatic quarter in capital Riyadh and Kuwait saying an attack hit fuel tanks at its international airport.

The health ministry said Sunday that an Israeli strike on a hotel in central Beirut killed at least four people, with Israel saying it had targeted commanders from Iran's Revolutionary Guards.

Lebanon was drawn into the Middle East war on Monday, when Hezbollah attacked Israel in response to the killing of Iranian supreme leader Ayatollah Ali Khamenei during U.S.-Israeli strikes.

The Israeli military on Saturday warned the remaining residents of Beirut's southern suburbs, where Hezbollah holds sway, to evacuate immediately.

Lebanese Army chief Rodolphe Haykal said Saturday that the Israeli soldiers who made helicopter landings in east Lebanon wore military uniforms similar to those of the Lebanese Army and used military vehicles and ambulances similar to those of the Hezbollah-linked Islamic Health Authority.

Haykal added that Israeli attacks targeting Lebanon were hindering the implementation of the army's plan to disarm Hezbollah.

Israel's military on Saturday warned residents in a district of Lebanon's Tyre to evacuate ahead of strikes, and reiterated a demand for people to leave the area south of the Litani River.

The Israeli military's strikes on east Lebanon, where Israeli forces carried out a commando operation, killed 41 people, the Lebanese health ministry said on Saturday.

The United Nations special coordinator for Lebanon on Saturday urged Lebanon and Israel to enter talks to negotiate an end to hostilities after the outbreak of a renewed Israel-Hezbollah war.

Israeli Defense Minister Israel Katz on Saturday warned President Joseph Aoun that Lebanon would pay a "very heavy price" if it fails to disarm Hezbollah.

U.S. President Donald Trump threatened to escalate the bombing of Iran on Saturday as Iranian President Masoud Pezeshkian vowed that he would never surrender, despite a fresh blitz of U.S. and Israeli air strikes that set a Tehran airport ablaze.

Israel confirmed some of the biggest raids since the aerial bombardment of Iran began last Saturday, with a military academy, an underground command center and a missile storage facility named as targets.

Israel's military said Saturday it had carried out an operation in east Lebanon to find remains of airman Ron Arad, but failed to uncover any trace of the navigator missing since 1986.